Download Aging: Facts and Theories by L. Robert, T. Fulop, T. Fulop PDF

By L. Robert, T. Fulop, T. Fulop

Getting older encouraged a number of theories attempting to rationalize the getting older approach universal to all dwelling beings. during this e-book an important environmental and intrinsic mechanisms all for the getting older strategy and in its pathological results are reviewed. moreover theoretical and experimental facts of crucial theoretical parts according to Darwinian evolution, mobile getting older, function of phone membranes, unfastened radicals and oxidative strategies, receptor-mediated reactions, the extracellular matrix and immune features in addition to an important environmental and intrinsic mechanisms concerned about the getting older method and in its pathological outcomes are mentioned. those displays of theories and comparable experimental evidence supply a world evaluation of latest options of the biology of the getting older procedure and are of crucial examining not just for experts during this box but additionally for practitioners of medical, clinical, social and experimental sciences.

Show description

Read Online or Download Aging: Facts and Theories PDF

Similar geriatrics books

Sleep Disorders and Neurologic Diseases,

Fullyyt dedicated to the connection among sleep and mind functionality, and the enhanced administration of sleep in sufferers with neurologic ailments, this thoroughly up to date moment variation contains new sections at the position of hypothalamic disorder in narcolepsy and the rising courting among sleep apnea and high blood pressure, middle affliction, and stroke.

The role of nutrition in maintaining health in the nation's elderly: evaluating coverage of nutrition services for the Medicare population

Malnutrition and weight problems are either universal between american citizens over age sixty five. There also are a bunch of different health conditions from which older humans and different Medicare beneficiaries undergo that may be more desirable with acceptable dietary intervention. regardless of that, entry to a nutrients specialist is especially restricted.

Prevention of Late-Life Depression: Current Clinical Challenges and Priorities

This ebook illustrates the vital for late-life melancholy prevention, introducing a wide variety of methods to prevention and offers distinct examples of scientific functions of late-life melancholy prevention – all with attention of scientific and clinical, social, financial and worldwide well-being views.

Designing technology training for older adults in continuing care retirement communities

This publication offers the newest learn and design-based strategies for a way to layout and enforce a know-how education software for older adults in carrying on with Care Retirement groups (CCRCs). The strategy within the booklet concentrates on delivering precious most sensible practices for CCRC proprietors, CEOs, job administrators, in addition to practitioners and method designers operating with older adults to reinforce their caliber of lifestyles.

Additional resources for Aging: Facts and Theories

Example text

Some of the distinctions between the fibroblasts from different tissues are probably necessary to provide for the metabolism of the respective organs and create the appropriate microenvironment. The need for the interaction between fibroblasts and other cell types during development is well known. Mouse embryo mammary rudiments fail to develop in the absence of mesenchyme; the instructive effect of mesenchyme on branching is specific since embryonic mammary epithelium exposed to salivary gland mesenchyme assumes a salivary-like branching [132].

2 Macieira-Coelho A, Pontén J, Philipson L: The division cycle and RNA synthesis in diploid human cells at different passage levels in vitro. Exp Cell Res 1966; 42:673–684. 3 Macieira-Coelho A, Berumen L: The cell cycle during growth inhibition of human embryonic fibroblasts in vitro. Proc Soc Exp Biol Med 1973;144: 43–47. 4 Macieira-Coelho A: Are non-dividing cells present in ageing cell cultures? Nature 1974;248: 421–422. 5 Absher PM, Absher RG: Clonal variation and aging of diploid fibroblasts.

Since it was thought that aging favors malignant transformation, speculations were made to find a relationship between ‘cell senescence’ and cancers, which led to several paradoxes. The contradictions and paradoxes should be cleared to reestablish logic and order in the field and understand its relevance for human aging. © 2014 S. Karger AG, Basel The Concept of Aging of Proliferative Cells The study of aging of proliferative cells was initiated by the work of Hayflick and Moorhead [1] who proposed that the loss of the division potential of human fibroblasts through proliferation in vitro is an expression of aging at the cellular level.

Download PDF sample

Rated 4.01 of 5 – based on 15 votes